CJC-1295 and ipamorelin act on two different receptors, which is exactly why they appear together in so many growth-axis assay designs.
CJC-1295 is a GHRH analog; ipamorelin is a selective ghrelin/GHS-R agonist. Because they engage distinct receptors, published in-vitro work commonly evaluates them together to observe complementary signalling rather than redundant activity.
DAC vs no-DAC
- CJC-1295 with DAC includes a drug-affinity complex that supports albumin binding and a substantially longer half-life.
- CJC-1295 no-DAC (mod GRF 1-29) has a short half-life and is favoured for pulsatile assay designs.
- Select the variant that matches your sampling schedule — mismatches are the most common protocol error we see.
Handling
- Store lyophilized vials at -4°F to 46°F (-20°C to 8°C), protected from light.
- Reconstitute with bacteriostatic water; add solvent slowly down the vial wall, never directly onto the pellet.
- Do not shake — swirl gently until fully dissolved.
- Once reconstituted, keep refrigerated and record the reconstitution date on the vial.
- Log the batch/lot number against the matching COA before any assay work begins.
Every Palm Valley Peptides lot ships from the USA with same-day dispatch on cleared orders, HPLC-MS purity documentation, and a batch-matched certificate of analysis.
Why is ipamorelin described as selective?
In published in-vitro work it shows minimal cross-activity at receptors targeted by earlier-generation GHRPs.



